ELK Biotechnology CDHF10 rabbit pAb
CDHF10(CELSR2) 단백질을 인식하는 토끼 다클론 항체로, IHC, IF, ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 세포막 단백질 분석에 유용합니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology CDHF10 Rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CDHF10 rabbit pAb |
| Alternative Names | CELSR2; CDHF10; EGFL2; KIAA0279; MEGF3; Cadherin EGF LAG seven-pass G-type receptor 2; Cadherin family member 10; Epidermal growth factor-like protein 2; EGF-like protein 2; Flamingo homolog 3; Multiple epidermal growth factor-like domains |
| Applications | IHC; IF; ELISA |
| Recommended Dilutions | IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/5000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human CELSR2 (AA range: 2781–2830) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 1952 |
| Human Swiss-Prot No. | Q9HCU4 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins, a subpopulation that does not interact with catenins. These cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats, and two laminin A G-type repeats in their ectodomain. They also possess seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins act as receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this member has not yet been determined.
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