ELK Biotechnology TdT rabbit pAb
TdT rabbit pAb는 인간, 랫트, 마우스 시료에서 사용 가능한 폴리클로날 항체로 WB, IHC, IF, ELISA에 적합합니다. 인간 DNTT 유래 펩타이드로 면역화되었으며, 핵에 발현되는 60kD 단백질을 검출합니다. -20°C에서 1년 보관 가능합니다.
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제품명
TdT rabbit pAb
대체 명칭
DNTT; TDT; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase; Terminal transferase
적용 분야 (Applications)
WB; IHC; IF; ELISA
권장 희석 배수 (Recommended Dilutions)
- IHC-p: 1:100–1:300
- Western Blot: 1:500–1:2000
- ELISA: 1:40000
- 다른 응용에는 아직 테스트되지 않음
면역원 (Immunogen)
The antiserum was produced against synthesized peptide derived from human DNTT.
Amino acid range: 381–430
보관 조건 (Storage)
-20°C / 1 year
항체 특성 (Antibody Characteristics)
| 항목 | 내용 |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| Gene ID (Human) | 1791 |
| Human Swiss-Prot No | P04053 |
| Cellular Localization | Nucleus |
| Species Reactivity | Human; Rat; Mouse |
배경 (Background)
This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3′-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
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