ELK Biotechnology p68 RNA Helicase (phospho Tyr593) rabbit pAb
인산화된 Tyr593 부위를 인식하는 p68 RNA Helicase (DDX5) 폴리클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에서 반응하며 핵 및 세포질에 위치한 단백질 검출에 유용합니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology p68 RNA Helicase (phospho Tyr593) rabbit pAb
제품 개요
p68 RNA Helicase (phospho Tyr593) rabbit polyclonal antibody는 인간 DDX5 단백질의 인산화 Tyr593 부위를 인식하는 항체로, 다양한 생물학적 시료에서 RNA helicase의 세포 내 발현 및 위치를 검출할 수 있습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | p68 RNA Helicase (phospho Tyr593) rabbit pAb |
| Alternative Names | DDX5; G17P1; HELR; HLR1; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC: 1/100–1/300 IF: 1/200–1/1000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human DDX5/DEAD-box Protein 5 around phosphorylation site of Tyr593 (AA range: 565–614) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 1655 |
| Human Swiss-Prot No | P17844 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | Nucleus, nucleolus, cytoplasm. During G0 phase predominantly nuclear; cytoplasmic levels increase during G1/S phase; during M phase located near condensed chromosomes; at G1, localizes in cytoplasm. |
Background
DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They participate in various cellular processes involving RNA secondary structure modification, including translation initiation, splicing, and ribosome assembly. Members of this family are associated with embryogenesis, spermatogenesis, and cell growth and division. The DDX5 gene encodes an RNA-dependent ATPase and a proliferation-associated nuclear antigen that reacts with the simian virus 40 tumor antigen. Alternative splicing produces multiple transcript variants. (RefSeq, Feb 2016)
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