ELK Biotechnology DD1 rabbit pAb
DD1 단백질을 인식하는 토끼 폴리클로날 항체로 IHC, IF, ELISA에 적합합니다. 세포질 내 DD1 단백질 검출용으로 사용되며, 인간·쥐·마우스 반응성이 있습니다. 고순도 IgG 형태로 -20°C에서 1년 보관 가능합니다.
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제품명
DD1 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | AKR1C1; DDH; DDH1; Aldo-keto reductase family 1 member C1; 20-alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; Chlordecone reductase homolog HAKRC; Dihydrodiol dehydrogenase 1/2; DD1/DD2; High-affinity hepatic bile acid-binding protein; HB |
| Applications | IHC, IF, ELISA |
| Recommended Dilutions | Immunohistochemistry: 1/100–1/300 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from DD1 (AA range: 30–110) |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 37 kD |
| GeneID (Human) | 1645 |
| Human Swiss-Prot No | Q04828 |
| Cellular Localization | Cytoplasm, cytosol |
| Species Reactivity | Human, Rat, Mouse |
배경 (Background)
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reaction of progesterone to the inactive form 20-alpha-hydroxy-progesterone. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. [provided by RefSeq, Jul 2008]
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