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ELK Biotechnology AR-α1A rabbit pAb
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ELK Biotechnology AR-α1A rabbit pAb

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Alpha-1A 아드레날린 수용체를 인식하는 토끼 폴리클로날 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트에 반응하며 핵막 및 세포막 단백질 검출에 적합. -20℃에서 1년 보관 가능.

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pk
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ELK Biotechnology ES4880-100UL AR-α1A rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES4880-50UL AR-α1A rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology AR-α1A rabbit pAb

제품명

AR-α1A rabbit pAb

제품 정보

항목 내용
Alternative Names ADRA1A; ADRA1C; Alpha-1A adrenergic receptor; Alpha-1A adrenoreceptor; Alpha-1A adrenoceptor; Alpha-1C adrenergic receptor; Alpha-adrenergic receptor 1c
Applications WB; IHC; IF; ELISA
Recommended Dilutions WB: 1/500–1/2000
IHC: 1/100–1/300
IF: 1/200–1/1000
ELISA: 1/10000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human ADRA1A (AA range: 341–390)
Host Rabbit
Storage -20°C, 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 51 kDa
Gene ID (Human) 148
Human Swiss-Prot No. P35348
Cellular Localization Nucleus membrane; Multi-pass membrane protein; Cell membrane; Cytoplasm; Membrane, caveola. Located at the nuclear membrane, facilitates heterooligomerization and regulates ERK-mediated signaling in cardiac myocytes. Colocalizes with GNAQ, PLCB1, and LAP2 at the nuclear membrane of cardiac myocytes.
Species Reactivity Human; Rat; Mouse

Background

Alpha-1-adrenergic receptors (α1-ARs) belong to the G protein-coupled receptor (GPCR) superfamily. They mediate mitogenic responses and regulate cell growth and proliferation. There are three α1-AR subtypes: α1A, α1B, and α1D, all signaling through the Gq/11 family of G-proteins. Each subtype exhibits distinct activation patterns. The ADRA1A gene encodes the alpha-1A-adrenergic receptor. Alternative splicing produces four transcript variants encoding isoforms with distinct C-termini but similar ligand-binding properties. (RefSeq, Jul 2008)

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