Thermo Fisher Scientific Hemoglobin alpha-1 Monoclonal Antibody (C5)
인간 Hemoglobin alpha-1을 인식하는 Mouse 모노클로날 항체(C5)로, WB 및 IHC(P) 분석에 적합. 고순도 Protein A/G 정제, 1 mg/mL 농도의 액상 형태. -20°C 보관, 연구용 전용.
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Applications
Western Blot (WB)
- Tested Dilution: 0.5–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 5–30 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | C5 |
| Immunogen | Recombinant protein Hemoglobin Alpha 1 (amino acids 1–142 of target protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.05% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899085 |
Target Information
The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3.
The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5untranslated regions and the introns, but they differ significantly over the 3 untranslated regions.
Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin.
Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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