Thermo Fisher Scientific FBXW2 Polyclonal Antibody
FBXW2 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체로, WB 및 IHC에 적합합니다. 인간, 생쥐, 랫트 반응성을 가지며, 고순도 정제 및 안정적 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific FBXW2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.3–1.5 µg/mL | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–3 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (KRGSSFLAGEHPG) corresponding to the C-terminus amino acids of FBXW2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10985918 |
Product Specific Information
- Predicted to react with bovine, canine, and porcine based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins are critical for the ubiquitin-mediated degradation of cellular regulatory proteins. F-box proteins form one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin-conjugating enzymes to substrates specifically recruited by different F-box proteins.
Mammalian F-box proteins are classified into three groups based on the presence of WD-40 repeats, leucine-rich repeats, or other protein-protein interaction domains.
The FBXW2 gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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