Thermo Fisher Scientific TGFBR2 Monoclonal Antibody (OTI3B4), TrueMAB
Human TGFBR2 단백질(aa 23-294)에 특이적인 Mouse IgG2a 단클론 항체. Western blot 및 IHC(P) 검증 완료. Lyophilized 형태로 제공되며, PBS buffer(8% trehalose) 포함. 연구용 전용 시약으로 세포 증식 조절 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 23–294 of human TGFBR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Transforming Growth Factor, beta receptor 2 (TGFBR2; also known as AAT3, FAA3, MFS2, RIIC, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII) is a member of the TGF-beta family of receptor Serine/Threonine kinases involved in the regulation of cell proliferation.
It encodes the gamma subunit of the catalytic core of mitochondrial ATP synthase, which catalyzes ATP synthesis utilizing the proton gradient across the inner membrane during oxidative phosphorylation.
Alternatively spliced transcript variants encoding different isoforms have been identified. TGFBR2 also has a pseudogene on chromosome 14.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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