Thermo Fisher Scientific EpCAM/CD326 (Epithelial Marker) Monoclonal Antibody (rEGP40/7334)
EpCAM/CD326 단일클론 항체로 상피세포 표지 및 암세포 연구에 적합함. IHC, Flow Cytometry 등 다양한 응용 가능. 인간, 개, 고양이 반응성. 단백질 A/G 정제, PBS 저장, 무보존제. 연구용 전용.
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Thermo Fisher Scientific EpCAM/CD326 (Epithelial Marker) Monoclonal Antibody (rEGP40/7334)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Dog, Cat, Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | rEGP40/7334 |
| Immunogen | Recombinant full-length human TACSTD1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Ep-CAM (epithelial adhesion molecule, epithelial specific antigen, ESA) is a transmembrane glycoprotein expressed in epithelial tissues (~40 kDa). It functions as a calcium-independent cell adhesion molecule and influences cell cycle, proliferation, and metabolism by inducing proto-oncogene c-myc and cyclins A and E.
Ep-CAM-mediated adhesions negatively regulate cadherin-mediated adhesions, affecting epithelial differentiation and growth. Overexpression is associated with increased epithelial proliferation and is highly expressed in human carcinomas, serving as a marker for epithelial-origin tumors.
Ep-CAM is localized on baso-lateral surfaces of simple epithelia and many carcinoma types and can distinguish adenocarcinomas from pleural mesotheliomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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