Thermo Fisher Scientific SR-BI Monoclonal Antibody (OTI1F3)
SR-BI 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 면역세포염색에 적합합니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제 및 안정한 PBS/BSA/glycerol 버퍼로 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:4,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Full length human recombinant protein of SCARB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725414 |
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism, and their plasma concentrations are inversely correlated with the risk for atherosclerosis.
SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. It is expressed primarily in the liver and nonplacental steroidogenic tissues, mediating cholesterol uptake by a distinct mechanism.
In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol storage in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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