Thermo Fisher Scientific Adenylate Kinase 2 Polyclonal Antibody
Thermo Fisher Scientific의 Adenylate Kinase 2 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 WB, IHC, ELISA에 사용 가능. Rabbit IgG 폴리클로날 항체로, 미토콘드리아 내막 공간의 AK2 단백질을 타겟. 고순도 친화 크로마토그래피 정제 및 안정한 PBS/glycerol 저장 조건 제공.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–232 of human AK2 (NP_0016161) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.56 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806595 |
Product Specific Information
Immunogen sequence:
MAPSVPAAEP EYPKGIRAVL LGPPGAGKGT QAPRLAENFC VCHLATGDML RAMVASGSEL GKKLKATMDA GKLVSDEMVV ELIEKNLETP LCKNGFLLDG FPRTVRQAEM LDDLMEKRKE KLDSVIEFSI PDSLLIRRIT GRLIHPKSGR SYHEEFNPPK EPMKDDITGE PLIRRSDDNE KALKIRLQAY HTQTTPLIEY YRKRGIHSAI DASQTPDVVF ASILAAFSKA TC
Positive Samples: HL-60, Mouse liver, Mouse kidney, Rat liver
Cellular Location: Mitochondrion intermembrane space
Target Information
Adenylate kinases regulate the adenine nucleotide composition within cells by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes (AK1, AK2, AK3) have been identified in vertebrates; this gene encodes isozyme 2. Expression is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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