Thermo Fisher Scientific RARG Monoclonal Antibody (OTI3G1), TrueMAB
Thermo Fisher Scientific의 RARG Monoclonal Antibody (OTI3G1)는 인간 RARG 단백질을 표적으로 하는 Mouse IgG1 항체입니다. Western blot에 1:2,000 희석 비율로 검증되었으며, 액상 형태로 제공됩니다. 높은 특이성과 안정성을 보장하며 연구용으로 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–223 of human RARG produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Retinoic acid, a metabolite of vitamin A, is essential for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. It functions through interaction with the nuclear protein retinoic acid receptor (RAR), which belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins. These receptors exert their effects by binding to specific DNA response elements, regulating gene expression in target cells.
RAR exists as three major subtypes: alpha, beta, and gamma. Two main isoforms of RAR gamma exist:
- RAR gamma-1: Predominantly expressed in skin
- RAR gamma-2: Found early in embryogenesis and in embryonal carcinoma cells
RAR gamma is also known as RARD. The corresponding gene for the retinoic acid receptor gamma 1 is NR1B3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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