Thermo Fisher Scientific CHRNA4 Polyclonal Antibody
CHRNA4 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 폴리클로날 항체. Western blot에 적합하며, 인간 및 랫트 반응성. 합성 펩타이드 면역원 사용, 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (HVETRAHAEERLLKK) corresponding to internal amino acids of CHRNA4 (aa 29–43) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10989292 |
Product Specific Information
- Predicted to react with bovine, canine, and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
- Not recommended for immunoprecipitation (IP).
Target Information
This gene encodes a nicotinic acetylcholine receptor, part of a superfamily of ligand-gated ion channels involved in fast synaptic transmission. These pentameric receptors bind acetylcholine, triggering conformational changes that open an ion-conducting channel across the plasma membrane. The CHRNA4 protein interacts with nAChR beta-2 or beta-4 subunits to form functional receptors. Mutations cause nocturnal frontal lobe epilepsy type 1, and certain polymorphisms provide protection against nicotine addiction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-19002_CHRNA4_P43681-1_Goat.svg, PA5-19002_CHRNA4_P43681-1_Goat_PDP.jpeg)
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