Thermo Fisher Scientific CD1a/HTA1 Recombinant Rabbit Monoclonal Antibody (C1A, 1506R)
Thermo Fisher Scientific의 CD1a/HTA1 재조합 토끼 단클론 항체(C1A, 1506R)는 인간 CD1a 단백질을 인식합니다. IHC(P) 및 Peptide Array에 사용 가능하며, 고순도의 Protein A 정제 항체입니다. PBS(pH 7.4) 용액 형태로 제공되며 방부제가 포함되지 않습니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | C1A, 1506R |
| Immunogen | Recombinant full-length human CD1a protein (UniProt ID: P06126-1, antigen range: 1–327) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed):
Incubate antibody for 30 minutes at room temperature.
Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CD1a is a non-polymorphic MHC Class I-related cell surface glycoprotein expressed in association with beta-2 microglobulin. It is found on cortical thymocytes, Langerhans cells, interdigitating cells, and certain T-cell malignancies.
CD1a participates in lipid and glycolipid antigen presentation to T cells and forms heterodimers with beta-2 microglobulin. The CD1 gene family (CD1a–e) is located on chromosome 1 and shows variation in subcellular localization and ligand specificity. CD1a localizes to the plasma membrane and early endocytic vesicles. Alternatively spliced transcript variants exist but their biological significance remains uncertain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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