Thermo Fisher Scientific Phospho-Proteasome 20S alpha 3 (Ser250) Polyclonal Antibody
Phospho-Proteasome 20S alpha 3 (Ser250) 인산화 부위를 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P)에서 사용 가능. Human, Mouse, Rat에 반응하며 Protein A로 정제된 액상 형태. -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Proteasome 20S alpha 3 around the phosphorylation site of Ser250 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core is composed of four rings of 28 non-identical subunits: two rings of seven alpha subunits and two rings of seven beta subunits. Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway. The immunoproteasome plays an essential role in processing class I MHC peptides. This gene encodes a member of the peptidase T1A family, a 20S core alpha subunit, with two alternative transcripts encoding different isoforms identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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