Thermo Fisher Scientific ITPKA Polyclonal Antibody
ITPKA 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. Human, Mouse, Rat 시료에 반응하며, Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA5101093
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ITPKA (Accession P23677), corresponding to amino acid residues L37–E87 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850537 |
Product Specific Information
Antibody detects endogenous levels of total IP3KA.
Target Information
ITPKA regulates inositol phosphate metabolism by phosphorylating the second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. This enzyme controls the levels of various inositol polyphosphates involved in cellular signaling. Its activity is regulated by calcium/calmodulin and protein phosphorylation mechanisms and serves as a substrate for cyclic AMP-dependent protein kinase, calcium/calmodulin-dependent protein kinase II, and protein kinase C in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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