Thermo Fisher Scientific NMDAR2D Polyclonal Antibody
NMDAR2D 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC에 사용 가능하며, 사람·생쥐·랫드 반응성. 동결건조 형태로 제공되며 장기 보관 시 -20°C 권장. 신경전달 및 뉴런 발달 연구에 적합.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from aa region 450–500 of mouse NMDAR2D conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and human.
- Specificity: NMDAR2D.
Target Information
Glutamate receptors mediate most excitatory neurotransmission in the brain and play a crucial role in neural plasticity, development, and neurodegeneration. Ionotropic glutamate receptors include NMDA and kainate/AMPA receptors, both forming glutamate-gated, cation-specific ion channels.
Kainate/AMPA receptors are primarily responsible for fast excitatory neurotransmission, while NMDA receptors show slower Ca²⁺ kinetics and high Ca²⁺ permeability.
NMDA receptors consist of five subunits: epsilon 1–4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem, while epsilon subunits show limited distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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