Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI1C8), TrueMAB
RALBP1 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, ICC/IF, Flow cytometry, IP 등 다양한 응용에 적합함. 인간 단백질에 특이적으로 반응하며, 고순도 친화 크로마토그래피 정제 제품. 연구용으로만 사용 가능.
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Thermo Fisher Scientific RALBP1 Monoclonal Antibody (OTI1C8), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 4 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C8 |
| Immunogen | Full length human recombinant protein of RALBP1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RALBP1 specifically activates hydrolysis of GTP bound to RAC1 and CDC42, but not RALA.
It mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX), serving as a major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
RALBP1 functions as a scaffold protein facilitating endocytotic complex formation and interacts with CDC2 to regulate endocytosis. One of its substrates is EPN1/Epsin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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