Thermo Fisher Scientific mGluR2 Polyclonal Antibody
Rabbit 폴리클로날 항체로 인간 mGluR2 검출에 사용. IHC(P)에서 1:100~1:200 희석으로 적용 가능. 비접합 액상 형태로 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장. 연구용 시약으로 신경전달 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide, KLH conjugated |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1957473 |
Product Specific Information
PA1-32825 detects GPRC1B from human samples.
Target Information
Glutamate is the main excitatory neurotransmitter in the brain. For many years, it had been considered to act only on ligand-gated receptor channels—termed NMDA, AMPA, and kainate receptors—that are involved in fast excitatory synaptic transmission.
Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins, called metabotropic glutamate receptors.
- Group-I receptors stimulate phospholipase C, increasing phosphoinositide turnover and calcium release from internal stores.
- Group-II and Group-III receptors inhibit adenylyl cyclase.
- Group-I receptors include mGluR1a and mGluR5.
- Group-II receptors include mGluR2 and mGluR3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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