Thermo Fisher Scientific PHF20 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PHF20. Recombinant protein control fragment (Product #RP-95252). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PHF20,uniProtId:Q9BVI0-1,ncbiNodeId:9606,antigenRange:537-638,antigenLength:1012,antigenImageFileName:PA5-56211_PHF20_Q9BVI0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-56211_PHF20_Q9BVI0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645487

Product Specific Information

Immunogen sequence: VRVKPKKKKK KKKKTKPECP CSEEISDTSQ EPSPPKAFAV TRCGSSHKPG VHMSPQLHGP ESGHHKGKVK ALEEDNLSES SSESFLWSDD EYGQDVDVTT NP

Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 90%.

Target Information

Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 Lys-16 acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.