Thermo Fisher Scientific PHF20 Polyclonal Antibody
인간 PHF20 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 1:200~1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 버퍼에 보존. 연구용으로 DNA 손상 후 p53 안정화 관련 연구에 적합.
- 카탈로그번호
- PA556211
- 판매단위
- pk
카탈로그
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Applications
Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PHF20 (Product #RP-95252) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645487 |
Product Specific Information
Immunogen sequence:
VRVKPKKKKK KKKKTKPECP CSEEISDTSQ EPSPPKAFAV TRCGSSHKPG VHMSPQLHGP ESGHHKGKVK ALEEDNLSES SSESFLWSDD EYGQDVDVTT NP
Highest antigen sequence identity to the following orthologs:
- Mouse: 90%
- Rat: 90%
Target Information
Methyllysine-binding protein and a component of the MOF histone acetyltransferase complex. Not required for maintaining global histone H4 Lys-16 acetylation (H4K16ac) levels or locus-specific histone acetylation, but functions downstream in transcriptional regulation of MOF target genes. As part of the NSL complex, it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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