Thermo Fisher Scientific POLR3F Polyclonal Antibody
인간 POLR3F 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:50–1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태로 제공. RNA polymerase III 관련 연구 및 HIV 의존 인자 연구에 적합.
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Applications
Tested Application
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human POLR3F. Recombinant protein control fragment (Product #RP-99440) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645772 |
Product Specific Information
Immunogen sequence:
VAINRLLSMG QLDLLRSNTG LLYRIKDSQN AGKMKGSDNQ EKLVYQIIED AGNKGIWSRD IRYKSNLPLT EINK
Antigen sequence identity:
- Mouse: 100%
- Rat: 100%
Target Information
The human POLR3F is a component of RNA polymerase III, which transcribes essential small noncoding RNAs such as 5S rRNAs and tRNAs. Many pol III-transcribed genes are spatially clustered near the nucleolus, potentially coordinating transcription with RNA polymerase I activity.
POLR3F has also been identified as an HIV dependency factor (HDF), suggesting its potential as a target in HIV research.
At least two isoforms of POLR3F are known to exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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