Thermo Fisher Scientific CDK2AP1 Polyclonal Antibody
CDK2AP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 세포주기 및 DNA 복제 조절 연구에 활용 가능. 비결합형 액상 형태로 -20°C에 보관.
- 판매단위
- pk
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Thermo Fisher Scientific CDK2AP1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:500–1:1,000
Publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human CDKA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555117 |
Target Information
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2)-associated protein that negatively regulates CDK2 activity by sequestering monomeric CDK2 and targeting CDK2 for proteolysis.
It also interacts with DNA polymerase alpha/primase and mediates phosphorylation of the large p180 subunit, suggesting a regulatory role in DNA replication during the S-phase.
Additionally, this protein forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex, which epigenetically regulates embryonic stem cell differentiation.
This gene plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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