Thermo Fisher Scientific GPR176 Polyclonal Antibody
Human GPR176 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, IHC(P) 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 비결합형 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human GPR176. Recombinant protein control fragment (Product #RP-102880). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642175 |
Product Specific Information
Immunogen sequence:
PPLSTVDSVS QVAPAAPVEP ETFPDKYSLQ FGFGPFELPP QWLSETRNSK KRLLPPLGNT PEELIQTKVP KVGRVERKMS RNNKV
Antigen sequence identity:
- Mouse: 85%
- Rat: 89%
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, are a superfamily of proteins involved in numerous stimulus-response pathways. They translate extracellular signals into intracellular responses via G protein activation and respond to various molecules such as hormones and neurotransmitters.
GPR176 (G protein-coupled receptor 176):
- Also known as HB-954, GPR, or Gm1012
- 515 amino acid multi-pass membrane protein
- Belongs to G-protein coupled receptor 1 family
- Expressed in brain and spleen, trace expression in kidney
- Functions as an orphan receptor involved in cellular signaling
- Contains four N-glycosylation sites, seven transmembrane domains, and a large C-terminal cytosolic domain
- Gene located on human chromosome 15q14
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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