Thermo Fisher Scientific SGPL1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SGPL1 C-terminal region. Validated for Western blot applications. High purity via affinity chromatography. Supplied in PBS with sucrose and sodium azide. Recommended storage at -20°C.
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- PA545795
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- pk
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Applications
- Western Blot (WB): Tested at 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human SGPL1 (aa 483–532) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609909 |
Product Specific Information
- Peptide Sequence: IHFCITLLHA RKRVAIQFLK DIRESVTQIM KNPKAKTTGM GAIYGMAQTT
- Sequence Homology:
Cow: 100%; Dog: 100%; Goat: 93%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 91%
Target Information
Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases such as sphingosine-1 phosphate into fatty aldehydes and phosphoethanolamine. It elevates stress-induced ceramide production and apoptosis. The enzyme uses pyridoxal phosphate as a co-factor and is a type III membrane protein found in the endoplasmic reticulum, primarily in the liver and kidney. It belongs to the group II decarboxylase family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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