
Thermo Fisher Scientific Phospho-Slingshot homolog 1 (Ser976) Polyclonal Antibody
Slingshot homolog 1 단백질의 Ser976 인산화 부위를 인식하는 Thermo Fisher Scientific의 다클론 항체입니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, 인간 및 설치류 등 다양한 종에 반응합니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 카탈로그번호
- PSISHT-140AP
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Phospho-Slingshot homolog 1 (Ser976) Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated synthetic peptide corresponding to unique amino acid sequence on Slingshot homolog 1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering chromatin structure.
The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin.
It possesses at least two conserved domains important for function:
- A DNA-binding domain that specifically binds AT-rich sequences recognized by SNF/SWI complex at the beta-globin locus.
- A C-terminal domain that stimulates glucocorticoid receptor-dependent transcriptional activation.
The protein may confer specificity to the SNF/SWI complex and recruit it to targets through protein-DNA or protein-protein interactions. Two transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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