Thermo Fisher Scientific MBL2 Monoclonal Antibody (14D12)
MBL2 단백질을 인식하는 Rat IgG2a 단클론 항체로, Western blot, IHC(F), ICC/IF, Inhibition assay에 사용 가능. 칼슘 의존적 결합 특성을 가지며, PBS + 0.1% BSA 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:50 |
| Inhibition Assays (IA) | 1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 14D12 |
| Immunogen | Purified MBL-C (target family: MBL2, UniProt ID: P41317-1, antigen range: 1–244) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3091116 |
Product Specific Information
The monoclonal antibody 14D12 is a calcium-dependent antibody.
Target Information
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose, and N-acetylglucosamine on various microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, apoptotic blebs, and necrotic cells—but not to early apoptotic cells—facilitating their uptake by macrophages. MBL2 may also bind DNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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