Thermo Fisher Scientific Bcl-3 Polyclonal Antibody
Rabbit Polyclonal Antibody against Human Bcl-3, validated for Western Blot applications. Targets amino acids 2–13 and 107–120 of Bcl3. Supplied as liquid, unconjugated form at 0.5 mg/mL. Suitable for research use in NF-kB pathway studies.
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Applications
- Western Blot (WB): Tested dilution 0.5–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptides corresponding to amino acids 2–13 and 107–120 of Human Bcl3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2063423 |
Product Specific Information
PA1-29817 detects Bcl3 from human samples.
Target Information
B cell Lymphoma 3 (Bcl-3) is a member of the IkB subfamily of inhibitors, which is part of the NF-kB transcription factor protein family. It is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells.
Bcl-3 has versatile functions such as:
- Cytoplasmic activation of p50 homodimers
- Translocation to the nucleus
- Modulation of transcriptional machinery in the nucleus
Bcl-3 activity often relies on nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(PA1-29817_BCL-3_P20749-1_Rabbit.svg)
(PA1-29817_BCL-3_P20749-1_Rabbit_PDP.jpeg)
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