Thermo Fisher Scientific FAM213A Polyclonal Antibody
FAM213A 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot 및 IHC(Paraffin)에 적합합니다. 인간과 랫드 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 세포의 산화환원 조절 및 염증 반응 연구에 유용합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FAM213A. Recombinant protein control fragment (Product # RP-90169) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2641377 |
Product Specific Information
Immunogen sequence:
KFYGPQRRKM MFMGFIRLGV WYNFFRAWNG GFSGNLEGEG FILGGVFVVG SGKQGILLEH REKEFGDKVN LLSVLEAAKM IKPQTLASEK
- Highest antigen sequence identity to the following orthologs:
- Mouse: 87%
- Rat: 83%
Target Information
Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071).
Acts as an antioxidant (PubMed:19951071, PubMed:26438880).
Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071).
May affect bone resorption and help to maintain bone mass (PubMed:19951071).
Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880).
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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