Thermo Fisher Scientific FAM213A Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FAM213A. Recombinant protein control fragment (Product #RP-90169). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FAM213A,uniProtId:Q9BRX8-1,ncbiNodeId:9606,antigenRange:139-228,antigenLength:229,antigenImageFileName:PA5-55109_FAM213A_Q9BRX8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55109_FAM213A_Q9BRX8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641377

Product Specific Information

Immunogen sequence: KFYGPQRRKM MFMGFIRLGV WYNFFRAWNG GFSGNLEGEG FILGGVFVVG SGKQGILLEH REKEFGDKVN LLSVLEAAKM IKPQTLASEK

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 83%.

Target Information

Involved in redox regulation of the cell (PubMed:26438880, PubMed:19951071). Acts as an antioxidant (PubMed:19951071, PubMed:26438880). Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation (PubMed:19951071). May affect bone resorption and help to maintain bone mass (PubMed:19951071). Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway (PubMed:26438880). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.