
Thermo Fisher Scientific NGB/neuroglobin Polyclonal Antibody
인간, 생쥐, 랫드에서 반응하는 Rabbit Polyclonal 항체로, Neuroglobin 단백질 검출용. IHC(P), IHC(F), ICC/IF, ELISA 등에 사용 가능. 고순도의 Protein A 정제 항체로 -20°C에서 보관. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse NGB, amino acids 51–151 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Globins are a superfamily of gas-binding heme proteins present in bacteria, protists, fungi, plants, and animals. They play diverse roles including binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide, and carbon monoxide.
Neuroglobin (Ngb) is a hexacoordinate hemoglobin predominantly expressed in the vertebrate brain, possibly enhancing oxygen supply to neural components. Its high oxygen affinity and presence in cerebral neurons suggest a role in neuronal responses to hypoxia or ischemia. In vitro neuronal hypoxia elevates neuroglobin levels, enhancing neuronal survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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