Thermo Fisher Scientific RbBP7 Polyclonal Antibody
RbBP7 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, IP 등 다양한 응용에 적합합니다. Human 및 Mouse에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C 보관, 연구용 전용 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:200–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200–1:1,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 375 and the C-terminus (residue 425) of Human Retinoblastoma Binding Protein 7 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections.
- Based on 100% sequence identity, this antibody is predicted to react with Rat and Orangutan.
Target Information
This protein is a ubiquitously expressed nuclear protein belonging to a conserved subfamily of WD-repeat proteins. It binds directly to retinoblastoma protein, regulating cell proliferation. It is a component of several histone deacetylase complexes, including the mSin3 co-repressor complex, and participates in chromatin assembly. The protein interacts with the BRCA1 tumor-suppressor gene and may play a role in regulating cell proliferation and differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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