Thermo Fisher Scientific Calcyclin Polyclonal Antibody
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Applications
Tested Dilution
Publications
Western Blot (WB)
1:1,000-1:5,000
Immunohistochemistry (Paraffin) (IHC (P))
1:200-1:1,000
Immunocytochemistry (ICC/IF)
1:100-1:500
Immunoprecipitation (IP)
0.5-1 µL/mg of lysate
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human Siah-interacting protein/CacyBP fragment
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2902431
Target Information
Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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