
Thermo Fisher Scientific HOXB2 (Transcription Factor) Monoclonal Antibody (PCRP-HOXB2-1F2)
HOXB2 단백질을 인식하는 Thermo Fisher Scientific의 Monoclonal Antibody로, WB, IHC, ICC, Flow 등 다양한 연구용 애플리케이션에 적합. 인간 특이적 반응성을 가지며, Protein A/G로 정제된 액상 형태. 신경 및 적혈구 발달 연구에 활용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2 µg/mL |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10^6 cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-HOXB2-1F2 |
| Immunogen | Recombinant fragment (aa114–220) of human HOXB2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Hoxb-1 maintains its function by acting very early during hindbrain neurogenesis to specify effectors of the sonic hedgehog and Mash1 signaling pathways.
Hoxb2 is a homeodomain protein important in neural development, also expressed during erythropoiesis, hindbrain development, and normal adult lung development.
Hoxb2 may modulate gamma-globin mRNA expression during development and differentiation, and plays an important role in patterning of hindbrain and pharyngeal arches in zebrafish.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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