
Thermo Fisher Scientific HKR1 Polyclonal Antibody
Human HKR1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에 최적화됨. KLH 결합 합성 펩타이드(aa 133-159)를 면역원으로 사용. Protein A 및 항원 친화 크로마토그래피로 정제. PBS(pH 7.4) 완충액에 0.09% sodium azide 포함.
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Applications
- Western Blot (WB): Tested dilution 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 133–159 amino acids from the N-terminal region of human HKR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A, Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2900932 |
Target Information
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins.
HKR1 (Krueppel-related zinc finger protein 1, zinc finger protein 875) is a 659 amino acid nuclear protein involved in transcriptional regulation. It exists as two alternatively spliced isoforms and belongs to the Krueppel C2H2-type zinc-finger protein family, containing thirteen C2H2-type zinc fingers and one KRAB domain. The HKR1 gene maps to human chromosome 19q13.12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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