Thermo Fisher Scientific Filamin B Monoclonal Antibody (GT1282)
Filamin B 단백질을 인식하는 Mouse monoclonal antibody (Clone GT1282). Western blot 및 IHC(P) 검증 완료. Human과 Rat에 반응하며, PBS buffer에 보존된 액상 형태. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | GT1282 |
| Immunogen | Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.83 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787172 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (98%), Rat (98%), Chicken (97%), Bovine (99%).
- Positive Control: 293T, A431, HeLa, HepG2.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
FOXK1 is expressed in these cells and regulates cell cycle progression through interaction with its downstream target, the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung, and thymus. It is predominantly expressed in many malignant tissues, such as tumors of the brain, colon, and lymph node.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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