Thermo Fisher Scientific FABP3 Recombinant Rabbit Monoclonal Antibody (ARC1302)
FABP3 단백질을 인식하는 토끼 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. HEK293 세포에서 발현된 재조합 항체이며, 고순도 친화 크로마토그래피로 정제되었습니다. PBS 기반 완충액에 보관되며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1302 |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 1–100 of human FABP3 (P05413) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849619 |
Product Specific Information
Immunogen sequence:
MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG
Target Information
Fatty acid binding proteins (FABP) are small (approximately 13–14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long-chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids.
There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks rapidly out of chemically damaged or dying cells due to its small size, leading to a rise in serum levels. Liver FABP is a sensitive marker for hepatocellular damage both in vitro and in vivo. Damaged tissues are characterized by absence or low presence of FABP, facilitating recognition of such areas. L-FABP is also a marker for rapid hepatocyte lysis in vitro (e.g., in toxicology assays) and for detection of liver damage during and after transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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