Thermo Fisher Scientific FABP3 Recombinant Rabbit Monoclonal Antibody (ARC1302)

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Immunogen sequence:
MVDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG

Target Information

Fatty acid binding proteins (FABP) are small (approximately 13–14 kDa) intracellular proteins with a high degree of tissue specificity. FABPs are a class of cytoplasmic proteins that bind long-chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids.

There are at least six distinct types of FABP, each showing a specific pattern of tissue expression. FABP leaks rapidly out of chemically damaged or dying cells due to its small size, leading to a rise in serum levels. Liver FABP is a sensitive marker for hepatocellular damage both in vitro and in vivo. Damaged tissues are characterized by absence or low presence of FABP, facilitating recognition of such areas. L-FABP is also a marker for rapid hepatocyte lysis in vitro (e.g., in toxicology assays) and for detection of liver damage during and after transplantation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.