Thermo Fisher Scientific PCDHGC3/PCDH2 Polyclonal Antibody
PCDHGC3/PCDH2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등에 사용 가능. Human, Mouse, Rat 반응성. Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human PCDHGC3/PCDH2, amino acids 251–350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The PCDHGC3/PCDH2 gene belongs to the protocadherin gamma gene cluster located on chromosome 5. This cluster exhibits an immunoglobulin-like organization and includes 22 genes divided into three subfamilies (A, B, and C).
Each variable region exon encodes the extracellular region with six cadherin ectodomains and a transmembrane region, while the constant region exons encode a shared cytoplasmic region.
These neural cadherin-like cell adhesion proteins are believed to play essential roles in establishing and maintaining specific neuronal connections in the brain.
Alternative splicing has been observed for the gamma cluster genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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