Thermo Fisher Scientific FNBP4 Polyclonal Antibody
Human FNBP4 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 세포골격 조절 및 소포 형성 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human FNBP4. Recombinant protein control fragment (Product #RP-97286). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2641692 |
Product Specific Information
Immunogen sequence:
STQTSGWQYD TQCSLAGVGI EMGDWQEVWD ENTGCYYYWN TQTNEVTWEL PQYLATQVQG LQHYQPSSVP GAETSFVVNT
Antigen sequence identity:
Mouse - 89%, Rat - 88%
Target Information
FNBP4 encodes a protein containing two tryptophan-rich WW domains that bind the proline-rich formin homology 1 domains of formin family proteins, suggesting a role in the regulation of cytoskeletal dynamics during cell division and migration.
It also binds intersectin family proteins, suggesting a role in maintaining membrane curvature at sites of nascent vesicle formation.
Naturally occurring mutations in this gene are associated with Waardenburg anophthalmia syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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