Thermo Fisher Scientific NKCC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting NKCC1 (SLC12A2) for IHC-P applications. Recognizes human and non-human primate species. Purified via antigen affinity chromatography, supplied in PBS with 0.1% sodium azide. Suitable for research use only.
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- PA533024
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- pk
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Applications
- Immunohistochemistry (Paraffin) (IHC-P): 7.5–10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from internal region of human SLC12A2 / NKCC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550485 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Monkey, Marmoset (100%)
- Bovine, Pig (89%)
- Ferret, Dog, Bat, Panda (83%)
Target Information
NKCC1 mediates sodium and chloride transport and reabsorption. It is a membrane protein important for maintaining ionic balance and cell volume. NKCC1 functions as an electrically silent transporter system and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been identified.
Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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