Thermo Fisher Scientific NKCC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

7.5-10 µg/mL

-

Product Specifications

Species Reactivity

Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 18 amino acid peptide from internal region of human SLC12A2 / NKCC1.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550485

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Bovine, Pig (89%) Ferret, Dog, Bat, Panda (83%).

Target Information

NKCC1 mediates sodium and chloride transport and reabsorption. NKCC1 is a membrane protein and is important in maintaining proper ionic balance and cell volume. NKCC1 is an electrically silent transporter system that mediates sodium and chloride reabsorption. Further, NKCC1 plays a vital role in the regulation of ionic balance and cell volume and is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for NKCC1. Diseases associated with SLC12A2 include Basosquamous Carcinoma and Metatypical Basal Cell Carcinoma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.