Thermo Fisher Scientific HEYL Monoclonal Antibody (2E12)
HEYL 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간 시료 반응성이 있으며, PBS 버퍼에 보존된 액상 형태입니다. 연구용으로만 사용되며, Notch 신호 조절 관련 연구에 활용 가능합니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2E12 |
| Immunogen | HEYL (NP_055386, 1–70 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKRPKEPSGS DGESDGPIDV GQEGQLSQMA RPLSTPSSSQ MQARKKRRGI IEKRRRDRIN SSLSELRRLV
Target Information
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors.
The encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members.
It is thought to be an effector of Notch signaling and a regulator of cell fate decisions.
Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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