
Thermo Fisher Scientific HHATL Monoclonal Antibody (2B7)
HHATL 단백질을 인식하는 Mouse IgG1 단일클론 항체로, ELISA에 최적화됨. Hedgehog 신호전달 관련 연구용으로 사용. 액상 형태로 보존제 없이 제공되며, -20°C에서 보관. 연구용 전용 제품.
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Thermo Fisher Scientific HHATL Monoclonal Antibody (2B7)
Applications
- ELISA (ELISA)
Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2B7 |
| Immunogen | HHATL (NP_065758.2, 157–206 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 KDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
LISWQSGFVT GTFDLQEVLF HGGSSFTVLR CTSFALESCA HPDRHYSLAD
Target Information
HHATL (Hedgehog Acyltransferase-Like) is a gene that codes for a protein involved in the regulation of Hedgehog signaling pathways.
HHATL is located on chromosome 7q36.3 and encodes a protein with an acyltransferase domain crucial for N-palmitoylation of Sonic Hedgehog (Shh), essential for proper signaling activity and distribution.
It participates in processes such as endoplasmic reticulum stress amelioration via autophagy and shows high expression in the heart, suggesting a role in cardiac development and function.
Dysfunction in HHATL may lead to anomalies in Hedgehog signaling, impacting developmental and cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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