Thermo Fisher Scientific TUSC2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human TUSC2. Recombinant protein control fragment (Product #RP-95276). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TUSC2,uniProtId:O75896-1,ncbiNodeId:9606,antigenRange:4-106,antigenLength:110,antigenImageFileName:PA5-110993_TUSC2_O75896-1_Rabbit.svg,antigenImageFileNamePDP:PA5-110993_TUSC2_O75896-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.10 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856404

Product Specific Information

Immunogen sequence: SGSKARGLWP FASAAGGGGS EAAGAEQALV RPRGRAVPPF VFTRRGSMFY DEDGDLAHEF YEETIVTKNG QKRAKLRRVH KNLIPQGIVK LDHPRIHVDF PVI

Target Information

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.