Thermo Fisher Scientific Calpain 9 Monoclonal Antibody (OTI2G1)
Calpain 9 단백질을 인식하는 mouse monoclonal antibody로, WB, IHC, ICC, Flow cytometry에 사용 가능. 인간 시료에 반응하며, 액상 형태로 제공. Affinity chromatography로 정제되어 높은 특이성과 안정성을 제공.
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G1 |
| Immunogen | Full-length human recombinant protein of CAPN9 produced in HEK293T cells (Calpain 9, UniProt ID: O14815-1, antigen range 1–690, antigen length 690) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.78 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722909 |
Target Information
Calpains are a well-conserved family of calcium-dependent cysteine proteases found ubiquitously in cells. These proteins form heterodimers consisting of a small invariant subunit and a variable large subunit. The large subunit contains a cysteine protease domain, and both subunits have calcium-binding domains. Calpains are implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.
Calpain 9 is predominantly expressed in the stomach and small intestine and may play specialized roles in the digestive tract. It has been associated with gastric cancer, and multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(관련 항원 구조 이미지: MA5-25741_Calpain_9_O14815-1_House_mouse.svg, MA5-25741_Calpain_9_O14815-1_House_mouse_PDP.jpeg)
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