Thermo Fisher Scientific Bcl11a Polyclonal Antibody
Rabbit 유래의 Bcl11a 폴리클로날 항체로 Western blot과 Immunoprecipitation에 적합. 인간 BCL11A 단백질의 N-말단(1–50) 영역을 항원으로 사용. 1 mg/mL 농도의 액상 형태로 제공되며 4°C 보관. 마우스와 교차 반응 가능성이 예측됨.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 1–50 of human B-cell CLL/Lymphoma 11A |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
This gene encodes a C2H2-type zinc-finger protein similar to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia and may function as a leukemia disease gene through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It may be involved in lymphoma pathogenesis, as translocations associated with B-cell malignancies can deregulate its expression. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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