Thermo Fisher Scientific PLA2G2F Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PLA2G2F (NP_073730.3, 1 a.a. approximately 211 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PLA2G2F,uniProtId:Q9BZM2-1,ncbiNodeId:9606,antigenRange:1-168,antigenLength:168,antigenImageFileName:H00064600-B01P_PLA2G2F_Q9BZM2-1_House_mouse.svg,antigenImageFileNamePDP:H00064600-B01P_PLA2G2F_Q9BZM2-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MADGAKANPK GFKKKVLDRC FSGWRGPRFG ASCPSRTSRS SLGMKKFFTV AILAGSVLST AHGSLLNLKA MVEAVTGRSA ILSFVGYGCY CGLGGRGQPK DEVDWCCHAH DCCYQELFDQ GCHPYVDHYD HTIENNTEIV CSDLNKTECD KQTCMCDKNM VLCLMNQTYR EEYRGFLNVY CQGPTPNCSI YEPPPEEVTC SHQSPAPPAP P

Target Information

May play a role in lipid mediator production in inflammatory conditions, by providing arachidonic acid to downstream cyclooxygenases and lipoxygenases. Phospholipase A2, which catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:11112443). Hydrolyzes phosphatidylethanolamine more efficiently than phosphatidylcholine, with only a modest preference for arachidonic acid versus linoelic acid at the sn-2 position. Comparable activity toward 1-palmitoyl-2-oleoyl-phosphatidylserine vesicles to that toward 1-palmitoyl-2-oleoyl-phosphatidylglycerol. Hydrolyzes phosphatidylglycerol versus phosphatidylcholine with a 15-fold preference (PubMed:11112443). [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.