Thermo Fisher Scientific CYP1A2 Monoclonal Antibody (OTI15E2), TrueMAB
CYP1A2 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, IHC, ICC/IF, Flow Cytometry에 적합합니다. 고순도 Affinity chromatography로 정제되었으며 PBS/BSA/glycerol buffer에 보존됩니다. 약물 대사 관련 연구용으로 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI15E2 |
| Immunogen | Full length human recombinant protein of human CYP1A2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. The protein localizes to the endoplasmic reticulum and its expression is induced by polycyclic aromatic hydrocarbons (PAHs), including those found in cigarette smoke. Although its endogenous substrate is unknown, CYP1A2 can metabolize certain PAHs to carcinogenic intermediates. Other xenobiotic substrates include caffeine, aflatoxin B1, and acetaminophen. The transcript contains four Alu sequences flanked by direct repeats in the 3′ untranslated region.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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