Thermo Fisher Scientific CCRL2 Polyclonal Antibody

Applications

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Peptide sequence: LSAQLVPSLC SAVFVIGVLD NLLVVLILVK YKGLKRVENI YLLNLAVSNL
• Sequence homology:
  • Cow: 77%
  • Guinea Pig: 86%
  • Horse: 93%
  • Human: 100%
  • Mouse: 100%
  • Rabbit: 90%
  • Rat: 82%

Target Information

CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, HCR, CRAM-A, or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif, which is important for signaling and ligand-binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins that play a major role in the chemotaxis of T cells and phagocytic cells to areas of inflammation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.