Thermo Fisher Scientific CCRL2 Polyclonal Antibody
CCRL2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, N-terminal 합성 펩타이드를 면역원으로 제작되었습니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human CCRL2 (aa 36–85) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2610520 |
Product Specific Information
- Peptide sequence: LSAQLVPSLC SAVFVIGVLD NLLVVLILVK YKGLKRVENI YLLNLAVSNL
- Sequence homology:
- Cow: 77%
- Guinea Pig: 86%
- Horse: 93%
- Human: 100%
- Mouse: 100%
- Rabbit: 90%
- Rat: 82%
Target Information
CCRL2 (C-C chemokine receptor-like 2), also known as chemokine receptor X, HCR, CRAM-A, or CRAM-B, is a seven-pass transmembrane protein expressed by monocytes, neutrophils, and dendritic cells of immune tissues (predominantly spleen, fetal liver, bone marrow, and lymph node).
It shares over 40% homology with other C-C chemokine receptors but lacks the conserved DRY motif, which is important for signaling and ligand-binding.
C-C chemokine receptors are G-protein coupled, seven-pass transmembrane domain proteins that play a major role in the chemotaxis of T cells and phagocytic cells to areas of inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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