Thermo Fisher Scientific TRIM21 Polyclonal Antibody
TRIM21 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제 및 안정적 PBS/glycerol 저장.
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Thermo Fisher Scientific TRIM21 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
| Immunoprecipitation (IP) | 0.5 µg–4 µg antibody for 200 µg–400 µg extracts |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 86–334 of human TRIM21/SS-A (NP_0031322) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855928 |
Product Specific Information
Immunogen Sequence:
GTQGERCAVH GERLHLFCEK DGKALCWVCA QSRKHRDHAM VPLEEAAQEY QEKLQVALGE LRRKQELAEK LEVEIAIKRA DWKKTVETQK SRIHAEFVQQ KNFLVEEEQR QLQELEKDER EQLRILGEKE AKLAQQSQAL QELISELDRR CHSSALELLQ EVIIVLERSE SWNLKDLDIT SPELRSVCHV PGLKKMLRTC AVHITLDPDT ANPWLILSED RRQVRLGDTQ QSIPGNEERF DSYPMVLGA
Target Information
This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains—a RING, a B-box type 1 and a B-box type 2—and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus and interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described, but only one full-length form has been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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