Thermo Fisher Scientific Epsin 2 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Epsin 2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Epsin 2,uniProtId:O95208-1,ncbiNodeId:9606,antigenRange:405-481,antigenLength:641,antigenImageFileName:PA5-62052_Epsin_2_O95208-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62052_Epsin_2_O95208-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

Lot-Specific

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641078

Product Specific Information

Immunogen sequence: PKNSDPWAAS QQPASSAGKR ASDAWGAVST TKPVSVSGSF ELFSNLNGTI KDDFSEFDNL RTSKKTAESV TSLPSQN

Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 77%.

Target Information

Epsin2 plays a role in the formation of clathrin-coated invaginations and endocytosis. It binds to EPS15 (via the NPF repeat domain), as well as to AP-2 and clathrin (via the DPW repeat domain). The protein resides in the cytoplasm, in punctate structures throughout the cell, associated with clathrin-coated vesicles, and is particularly concentrated in the region of the Golgi complex. Highest expression is found in brain, with lower levels detected in lung and liver.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.