Thermo Fisher Scientific ARMS Polyclonal Antibody
Rabbit 유래 다클론 항체로, 인간 Ankyrin Repeat-Rich Membrane Spanning 단백질(ARMS)을 인식합니다. Western blot 및 Immunoprecipitation에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 4°C에서 보관하며 신경계 관련 단백질 연구에 활용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1400 and 1450 of human Ankyrin Repeat-Rich Membrane Spanning (KIDINS220, UniProt ID: Q9ULH0-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
This gene encodes a transmembrane protein that is preferentially expressed in the nervous system where it controls neuronal cell survival, differentiation into axons and dendrites, and synaptic plasticity. The encoded protein interacts with membrane receptors, cytosolic signaling components, and cytoskeletal proteins, serving as a scaffold that mediates crosstalk between the neurotrophin pathway and several other intracellular signaling pathways. Aberrant expression of this gene is associated with various neuropsychiatric and neurodegenerative diseases, including Alzheimer’s disease. Naturally occurring mutations in this gene are linked to a syndrome characterized by spastic paraplegia, intellectual disability, nystagmus, and obesity. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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