Thermo Scientific™

Pierce™ Traut`s Reagent (2-iminothiolane)

Thermo Scientific Pierce Traut`s Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains)자세히 알아보기

Thermo Scientific Pierce Traut`s Reagent (2-iminothiolane) is a small thiolation compound that reacts with primary amines (e.g., lysine side chains) to add a small spacer arm (8.1 angstroms) terminated by a free sulfhydryl group.

Features of Thermo Scientific Pierce Traut`s Reagent (2-iminothiolane):

• Simple—one-step conversion of amines to sulfhydryls
• Specific—selective and spontaneous modification of primary amines at pH 7-10
• Preserves positive charge to maintain protein solubility

Trauts Reagent (2-iminothiolane or 2-IT) is a cyclic thioimidate compound for thiolation (sulfhydryl addition). Trauts Reagent reacts with primary amines (—NH2) to introduce sulfhydryl (—SH) groups while maintaining charge properties similar to the original amino group. Once added, sulfhydryl groups can be specifically targeted for reaction in a variety of useful labeling, crosslinking and immobilization procedures.

Flexible—incorporates a five-atom spacer arm to reduce steric hindrance
• Soluble—preserves the original positive charge to preserve protein solubility

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Pierce™ SATA

사양

화학물질 반응성Amine

라벨 또는 염료Sulfhydryl Group

라벨 유형Conjugating Groups

제품라인Pierce™

스페이서Short (<10 Å)

형태Powder

수량500 mg

용해도DMF, DMSO

제품 유형Thiophilic Adsorption Kit

Unit SizeEach